A multi-component domino reaction for the direct access to polyfunctionalized indoles via intermolecular allylic esterification and indolation.
نویسندگان
چکیده
A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15-30 min with water as the major byproduct, which makes work-up convenient.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 6 شماره
صفحات -
تاریخ انتشار 2012